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Cutaneous squamous-cell carcinoma is the second-most common cancer of the skin (after basal-cell carcinoma, but more common than melanoma). It usually occurs in areas exposed to the sun. Sunlight exposure and immunosuppression are risk factors for SCC of the skin, with chronic sun exposure being the strongest environmental risk factor. [26]
Of nonmelanoma skin cancers, about 80% are basal-cell cancers and 20% squamous-cell skin cancers. [14] Basal-cell and squamous-cell skin cancers rarely result in death. [6] In the United States, they were the cause of less than 0.1% of all cancer deaths. [1] Globally in 2012, melanoma occurred in 232,000 people and resulted in 55,000 deaths. [6]
Mast cell: Mastocytosis: Bcl-2: Basal cell carcinoma Primary cutaneous marginal zone lymphoma Diffuse large B-cell lymphoma leg type: Bcl-6: Primary cutaneous follicular lymphoma: BerEp4: Desmoplastic trichoepithelioma Basal cell carcinoma: Brown–Brenn: Eumycotic mycetoma: CAM 5.2: Merkel cell carcinoma: CCR7: Melanoma: Carcinoembryonic ...
Conditions of or affecting the human integumentary system associated with increased risk of nonmelanoma skin cancer Condition Squamous-cell carcinoma Basal-cell carcinoma; Xeroderma pigmentosum + + Oculocutaneous albinism + + Epidermodysplasia verruciformis + Recessive dystrophic epidermolysis bullosa + Ferguson–Smith syndrome + Muir–Torre ...
Basal-cell carcinoma (BCC), also known as basal-cell cancer, basalioma [7] or rodent ulcer, [8] is the most common type of skin cancer. [2] It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it . [ 1 ]
Not all basal-cell cancers originate in the basal cells but they are so named because the cancer cells resemble basal cells when seen under a microscope. [ 4 ] In a growing fetus, fingerprints form where the cells of the stratum basale meet the papillae of the underlying papillary layer of the dermis , resulting in the formation of the ridges ...
Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. [1] These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts .
Found in the lowest layer of the epidermis, the stratum basale, basal cells continuously divide in order to replenish the squamous cells that make up the skin's surface. [6] Every time a basal cell divides, it creates two daughter cells, one is an identical basal cell, and the other is a new somatic cell that undergoes terminal differentiation ...