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Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...
It is important to note that symptoms related to infectious mononucleosis caused by EBV infection seldom last for more than 4 months. When such an illness lasts more than 6 months, it is frequently called chronic EBV infection. However, valid laboratory evidence for continued active EBV infection is seldom found in these patients.
Many children who become infected with EBV display no symptoms or the symptoms are indistinguishable from the other mild, brief illnesses of childhood. [21] When infection occurs during adolescence or young adulthood, it causes infectious mononucleosis 35 to 50% of the time. [22] EBV infects B cells of the immune system and epithelial cells.
How long do symptoms last? They peak at 24 to 48 hours but can last up to 72 hours, says Dr. Dibba. Norovirus tends to hit hard and then fade fairly quickly. Symptoms do ramp up in intensity, however.
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Mononucleosis is among the best studied, and available studies found that 7-9% had persistent symptoms 12 months after infection, and 4% had serious symptoms after 2 years. The British Office of National Statistics data on long COVID say that about 10% of people who had COVID-19 self-reported long COVID 6 months after infection, and about 7% ...
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It will generally not be positive during the 4–6 week incubation period before the onset of symptoms. The highest amount of heterophile antibodies occurs 2 to 5 weeks after the onset of symptoms. [9] If positive, it will remain so for at least six weeks. [10] An elevated heterophile antibody level may persist up to 1 year. [9]