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Precision diagnostics is a branch of precision medicine that involves managing a patient's healthcare model and diagnosing specific diseases based on omics data analytics. [1] The U.S. announced federal funding for precision medicine research efforts in 2015 with the Precision Medicine Initiative. A year later, the Human Personal Omics ...
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
It was the world’s first “rapid home test” that gave pregnancy test results in 30 minutes and allowed a woman to take a test before going to the doctor. [4] The test was a three-step process using a dipstick and small tray. [4] In 1988, Clearblue launched the first one-step pregnancy test with the invention of lateral flow technology.
One of the most important roles of LC-MS and LC-MS/MS in the clinical lab is the Newborn Screening (NBS) for metabolic disorders [81] and follow-up diagnostics. [82] [83] The infants' samples come in the shape of dried blood spot (DBS), [84] which is simple to prepare and transport, enabling safe and accessible diagnostics, both locally and ...
A general procedure for HA is as follows, a serial dilution of virus is prepared across the rows in a U or V- bottom shaped 96-well microtiter plate. [5] The most concentrated sample in the first well is often diluted to be 1/5x of the stock, and subsequent wells are typically two-fold dilutions (1/10, 1/20, 1/40, etc.).
Because of the complex inter-relationship between analytical method, sample concentration, limits of detection and method precision, the management of Analytical Quality Control is undertaken using a statistical approach to determine whether the results obtained lie within an acceptable statistical envelope.
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Alere Inc. was a global manufacturer of rapid point-of-care diagnostic tests.The company was founded in 1991 and was headquartered in Waltham, Massachusetts. [2] [3] As of January 2017, the company had a market capitalization of $3.47 billion with an enterprise value of $5.9 billion. [1]