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Sex differences in human physiology are distinctions of physiological characteristics associated with either male or female humans. These differences are caused by the effects of the different sex chromosome complement in males and females, and differential exposure to gonadal sex hormones during development.
In the absence of a Y chromosome, the fetus will undergo female development. This is because of the presence of the sex-determining region of the Y chromosome, also known as the SRY gene. [5] Thus, male mammals typically have an X and a Y chromosome (XY), while female mammals typically have two X chromosomes (XX).
Sex differences in human physiology are distinctions of physiological characteristics associated with either male or female humans. These can be of several types, including direct and indirect, direct being the direct result of differences prescribed by the Y-chromosome (due to the SRY gene ), and indirect being characteristics influenced ...
The common pathway of sexual differentiation, where a productive human female has an XX chromosome pair, and a productive male has an XY pair, is relevant to the development of intersex conditions. During fertilization, the sperm adds either an X (female) or a Y (male) chromosome to the X in the ovum. This determines the genetic sex of the embryo.
Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote. [1] [2] Sex determination is often distinct from sex differentiation; sex determination is the designation for the development stage towards either male or female, while sex differentiation is the pathway towards the development of the phenotype.
Phenotypic differences between sexes are evident even in cultured cells from tissues. [132] For example, female muscle-derived stem cells have a better muscle regeneration efficiency than male ones. [133] There are reports of several metabolic differences between male and female cells [134] and they also respond to stress differently. [135]
After examination, it was discovered that the difference between a typical XX individual (traditional female) and a sex-reversed XX man was that the typical individuals lacked the SRY gene. It is theorized that in sex-reversed XX men, the SRY gets translocated to an X chromosome in the XX pair during meiosis. [8]
Male primary sex characteristics are the penis, the scrotum and the ability to ejaculate when matured. Female primary sex characteristics are the vulva, vagina, uterus, fallopian tubes, cervix, and the ability to give birth and menstruate when matured. [1] Hormones that express sexual differentiation in humans include: estrogens such as estradiol