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Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure in the arteries of the lungs. [ 7 ] Symptoms include shortness of breath, fainting, tiredness, chest pain, swelling of the legs, and a fast heartbeat. [ 7 ][ 1 ] The condition may make it difficult to exercise. [ 7 ] Onset is typically gradual. [ 8 ]
Riociguat, sold under the brand name Adempas, is a medication by Bayer that is a stimulator of soluble guanylate cyclase (sGC). It is used to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of the class of sGC ...
The Cambridge Pulmonary Hypertension Outcome Review has been a useful tool in clinical trials as it allows researchers to assess whether new medication or therapy is effective. The CAMPHOR has been utilized in clinical trials which investigate the effects of treprostinil, [12] [13] as well as trials which investigate sildenafil. [14] [15]
A 10-month NBC News investigation laid out in stark detail how two of the country’s most populous counties sent unclaimed bodies to a Texas medical school, which used them for medical training ...
Chronic thromboembolic pulmonary hypertension. Chronic thromboembolic pulmonary hypertension (CTEPH) is a long-term disease caused by a blockage in the blood vessels that deliver blood from the heart to the lungs (the pulmonary arterial tree). These blockages cause increased resistance to flow in the pulmonary arterial tree which in turn leads ...
Portopulmonary hypertension. Portopulmonary hypertension (PPH)[1] is defined by the coexistence of portal and pulmonary hypertension. PPH is a serious complication of liver disease, present in 0.25 to 4% of all patients with cirrhosis. Once an absolute contraindication to liver transplantation, it is no longer, thanks to rapid advances in the ...
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