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Diethyl phthalate (DEP) is a phthalate ester. It is a colourless liquid without significant odour but with a bitter disagreeable taste. Synthesis and applications
The most common way to prepare cellulose acetate phthalate consists of the reaction of a partially substituted cellulose acetate (CA) with phthalic anhydride in the presence of an organic solvent and a basic catalyst. The organic solvents widely used as reaction media for the phthaloylation of cellulose acetate are acetic acid, acetone, or ...
It can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications, e.g. as a plasticizer for film coating of tablets, beads, and granules. [2]
This page was last edited on 19 May 2018, at 05:23 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply ...
Phthalates can plasticise ethyl cellulose, polyvinyl acetate phthalate (PVAP) and cellulose acetate phthalate (CAP), all of which are used to make enteric coatings for tablet and capsule medications. These coatings protect drugs from the acidity of the stomach, but allow their release and absorption in the intestines.
Glycerol, Propylene glycol, low molecular weight polyethylene glycols, phthalate derivatives like dimethyl, diethyl and dibutyl phthalate, Citrate derivatives such as tributyl, triethyl, acetyl citrate, triacetin and castor oil are some of the commonly used plasticizer excipients.
[1] [2] In Ireland and the UK, the comparable preparation is surgical spirit B.P., which the British Pharmacopoeia defines as 95% methylated spirit, 2.5% castor oil, 2% diethyl phthalate, and 0.5% methyl salicylate. [3] Under its alternative name of "wintergreen oil", methyl salicylate is a common additive to North American rubbing alcohol ...
Bis(2-ethylhexyl) phthalate (DEHP) also commonly known as (dioctyl phthalate, [12] DOP or diethylhexyl phthalate), historically used in flooring materials, medical devices, myriad consumer products, and high explosives, such as Semtex. DEHP was the most common plasticizer for decades and still holds that title globally even as it has largely ...