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The substance received more credit when NASA chose it as a space antiemetic for the first crewed Moon flight. Cyclizine was introduced to many countries as a common antiemetic. It is an over-the-counter drug in many countries because it has been well tolerated, although it has not been studied much. [13] [15]
Syrup of ipecac (/ ˈ ɪ p ɪ k æ k /), or simply ipecac, is a drug that was once widely used as an expectorant (in low doses) and a rapid-acting emetic (in higher doses). It is obtained from the dried rhizome and roots of the ipecacuanha plant (Carapichea ipecacuanha), from which it derives its name.
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]
In the UK there are only two other combination analgesics with antiemetics (i.e., anti-nausea) products available: MigraMax (aspirin with metoclopramide) and the over-the-counter drug Migraleve (paracetamol and codeine for analgesia, with buclizine as the antiemetic). [6]
The antiemetic action of metoclopramide is due to its antagonist activity at D 2 receptors in the chemoreceptor trigger zone in the brain — this action prevents nausea and vomiting triggered by most stimuli. [34] At higher doses, 5-HT 3 antagonist activity may also contribute to the antiemetic effect. [35] [failed verification]
Over-the-counter (OTC) medicines at FamilyDoctor.org, maintained by the American Academy of Family Physicians. Contains extensive information on over-the-counter drugs and their responsible use, including specific guidance on several drug classes in question-and-answer format and information on common drug interactions.
The Joint Counter Terrorism Team (JTT) operation, which involved 13 raids in Sydney and the regional town of Goulburn, was a combined effort between state and federal police as well as the ...
Chlorpromazine may be used as an antiemetic in dogs and cats, or, less often, as a sedative before anesthesia. [73] In horses, it often causes ataxia and lethargy and is therefore seldom used. [72] [73] It is commonly used to decrease nausea in animals that are too young for other common antiemetics.