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In genetics, underdominance, also known as homozygote advantage, heterozygote disadvantage, or negative overdominance," [1] is the opposite of overdominance. It is the selection against the heterozygote , causing disruptive selection [ 2 ] and divergent genotypes .
Autosomal dominant and autosomal recessive inheritance, the two most common Mendelian inheritance patterns. An autosome is any chromosome other than a sex chromosome.. In genetics, dominance is the phenomenon of one variant of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome.
Pseudodominance is the situation in which the inheritance of a recessive trait mimics a dominant pattern. [1]Normally, two recessive alleles need to be inherited (one from each parent) for the recessive trait to be expressed but recessive merely means that the trait is only expressed in the absence of the dominant alleles.
An example in dog coat genetics is the homozygosity with the allele "e e" on the Extension-locus making it impossible to produce any other pigment than pheomelanin. Although the allele "e" is a recessive allele on the extension-locus itself, the presence of two copies leverages the dominance of other coat colour genes.
Overdominance is a phenomenon in genetics where the phenotype of the heterozygote lies outside the phenotypical range of both homozygous parents. Overdominance can also be described as heterozygote advantage regulated by a single genomic locus, wherein heterozygous individuals have a higher fitness than homozygous individuals.
The opposite situation, where all genes show dominance in the same direction, is called directional dominance. [1] In the same example, for both genes A and B increased height is dominant. According to Broadhurst, ambidirectional dominance is the result of stabilising selection in the evolutionary past. [ 1 ]
Two Oscars experts shared their insights on who gets to get dressed up: Michael Schulman, New Yorker writer and author of “Oscar Wars: A History of Hollywood in Gold, Sweat, and Tears,” and ...
Genetic variance has three major components: the additive genetic variance, dominance variance, and epistatic variance. [3] Additive genetic variance involves the inheritance of a particular allele from your parent and this allele's independent effect on the specific phenotype, which will cause the phenotype deviation from the mean phenotype.