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Live attenuated influenza vaccine (LAIV) is a type of influenza vaccine in the form of a nasal spray that is recommended for the prevention of influenza. [ 2 ] [ 7 ] It is an attenuated live vaccine, unlike other influenza vaccines, which are inactivated vaccines .
FluMist is a live attenuated flu vaccine, which means it uses a weakened version of the flu. (The flu shot, on the other hand, does not use a live version of the flu.)
What is the at-home nasal flu vaccine? FluMist is a quadrivalent live attenuated influenza vaccine (LAIV) administered as a nasal spray, says Ravi Jhaveri, M.D., division head and professor in ...
The FDA also says that people with weakened immune systems and certain allergies should not take FluMist and other live-attenuated virus vaccines. It’s not approved for use in people age 50 and ...
The CDC indicated that live attenuated influenza vaccine (LAIV), also called the nasal spray vaccine, was not recommended for the 2016–2017 flu season in the United States. [208] Furthermore, the CDC recommends that healthcare personnel who care for severely immunocompromised persons receive injections (TIV or QIV) rather than LAIV. [209]
The first live attenuated influenza vaccine (LAIV) in the form of a nasal spray was created in Russia by the Institute of Experimental Medicine in 1987. This nasal vaccine development was based on the Russian backbone of LAIV while nasal vaccines since then have been based on other LAIV backbones. [ 3 ]
For example, the live attenuated influenza vaccine is given nasally and is associated with nasal congestion. [25] Compared to inactivated vaccines, live-attenuated vaccines are more prone to immunization errors as they must be kept under strict conditions during the cold chain and carefully prepared (e.g., during reconstitution). [3] [22] [23]
The FluMist vaccine is a live attenuated vaccine (meaning, ... The most effective the flu vaccine has been in recent history was during the 2010-2011 season, when it was 60% effective.
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