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[3] [4] [5] Amphipols can be used to fold denatured membrane proteins to their native form [6] [7] and have proven particularly precious in the field of single-particle electron cryo-microscopy (cryo-EM; see e.g. [8] [9]).The properties and uses of amphipols and other non-conventional surfactants are the subject of a book by Jean-Luc Popot. [10]
In chemistry, an amphiphile (from Greek αμφις (amphis) 'both' and φιλíα 'love, friendship'), or amphipath, is a chemical compound possessing both hydrophilic (water-loving, polar) and lipophilic (fat-loving, nonpolar) properties. [1] Such a compound is called amphiphilic or amphipathic.
A typical amphiphilic flexible surfactant can form aggregates through a self-assembly process that results of specific interactions between the molecules of the amphiphilic mesogen and those of the non-mesogenic solvent. In aqueous media, the driving force of the aggregation is the "hydrophobic effect". The aggregates formed by amphiphilic ...
Micelle (polymers) Organized auto-assembly formed in a liquid and composed of amphiphilic macromolecules, in general amphiphilic di- or tri-block copolymers made of solvophilic and solvophobic blocks. Note 1: An amphiphilic behavior can be observed for water and an organic solvent or between two organic solvents. Note 2
Peptide amphiphiles were developed in the 1990s. They were first described by the group of Matthew Tirrell in 1995. [5] [6] These first reported PA molecules were composed of two domains: one of lipophilic character and another of hydrophilic properties, which allowed self-assembly into sphere-like supramolecular structures as a result of the association of the lipophilic domains away from the ...
Nanoparticle monolayers can be used to create functional surfaces that have for instance anti-reflective or superhydrophobic properties. [2] [3] Monolayers are frequently encountered in biology. A micelle is a monolayer, and the phospholipid lipid bilayer structure of biological membranes is technically two monolayers. Langmuir monolayers are ...
Because of their amphiphilic structures, the polymers have surfactant properties that make them useful in industrial applications. Among other things, they can be used to increase the water solubility of hydrophobic, oily substances or otherwise increase the miscibility of two substances with different hydrophobicities.
Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties that make it useful as a detergent. SDS is also component of mixtures produced from inexpensive coconut and palm oils. SDS is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as ...