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Sorafenib, sold under the brand name Nexavar, [3] is a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma.
Sorafenib is a small molecule inhibitor of many tyrosine kinase receptors such as VEGFR-2. Side effects are in most cases mild to moderate such as rash, hand-foot skin reaction, diarrhea and dermatitis, and occur in about 33-38% patients using sorafenib. Other side effects are mild hypertension, leukopenia and bleeding. Uncommon side effects ...
Bayer Healthcare and Onyx Pharmaceuticals announced today that the FDA has bumped up their oral multi-kinase inhibitor Nexavar (sorafenib) tablets assessment to priority review, promising a ...
Sunitinib is approved for the treatment of metastatic renal cell carcinoma. Other therapeutic options in this setting are pazopanib (Votrient), sorafenib (Nexavar), temsirolimus (Torisel), interleukin-2 (Proleukin), everolimus (Afinitor), bevacizumab (Avastin), and aldesleukin. Renal cell carcinoma is generally resistant to chemotherapy or ...
Research on the pain-relieving and infection-preventing effects of castor oil is also limited. Despite its ancient history and the abundance of anecdotes about castor oil's other uses, research is ...
Lighter Side. Politics. Science & Tech. Sports. Weather. 24/7 Help. For premium support please call: ... Small Washington town grapples with effects of french fry plant closure. Finance.
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