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The parahippocampal gyrus (or hippocampal gyrus [1]) is a grey matter cortical region of the brain that surrounds the hippocampus and is part of the limbic system. The region plays an important role in memory encoding and retrieval. It has been involved in some cases of hippocampal sclerosis. [2] Asymmetry has been observed in schizophrenia. [3]
The uncus is an anterior extremity of the parahippocampal gyrus.It is separated from the apex of the temporal lobe by a sulcus called the rhinal sulcus. [1] Although superficially continuous with the hippocampal gyrus, the uncus forms morphologically a part of the rhinencephalon.
Area 27 of Brodmann-1909 is a cytoarchitecturally defined cortical area that is a rostral part of the parahippocampal gyrus.It is commonly regarded as a synonym of presubiculum.
While many of the connections in non-human primates may be present in humans, they are less well documented. Studies have shown strong reciprocal connections to medial temporal lobe memory structures, such as the entorhinal cortex and the parahippocampal gyrus, the latter being involved in associative learning and episodic memory. [6]
Broca named the limbic lobe in 1878, identifying it with the cingulate and parahippocampal gyri, and associating it with the sense of smell - Treviranus having earlier noted that, between species, the size of the parahippocampal gyrus varies with the size of the olfactory nerve. [2]
In human anatomy, the piriform cortex has been described as consisting of the cortical amygdala, uncus, and anterior parahippocampal gyrus. [1] More specifically, the human piriform cortex is located between the insula and the temporal lobe, anteriorly and laterally of the amygdala. [2] [3]
The posterior cingulate cortex (Brodmann's area 23) sends projections to dorsolateral prefrontal cortex (Brodmann's area 9), anterior prefrontal cortex (Brodmann's area 10), orbitofrontal cortex (Brodmanns’ area 11), the parahippocampal gyrus, posterior part of the inferior parietal lobule, the presubiculum, the superior temporal sulcus and ...
Middle-posterior part of the cingulate gyrus and sulcus MTG: Middle temporal gyrus OcPo: Occipital pole OrG: Orbital gyri: OrS: Orbital sulci (H-shaped sulci) PaCL/S: Paracentral lobule and sulcus PaHipG: Parahippocampal gyrus, parahippocampal part of the medial occipito-temporal gyrus PerCaS: Pericallosal sulcus (S of corpus callosum) POcS