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Alosetron, sold under the brand name Lotronex among others, is a 5-HT 3 antagonist used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in females only. It was patented in 1987 and approved for medical use in 2002. [ 2 ]
Alosetron (Lotronex) 2000 US Serious gastrointestinal adverse events; ... Hepatotoxicity, dermatological side effects, and abuse potential. [7] Aminopyrine: 1999
Alosetron was withdrawn from the U.S. market in 2000 due to unacceptably frequent severe side effects, including ischemic colitis, and is only available through a restrictive program to patients who meet certain requirements. [23]
A study confirmed that side effects like pancreatitis and kidney damage are possible while taking GLP-1s like Ozempic. Here's what a doctor wants you to know.
Side effects include irregular heartbeat, fatigue, high blood pressure, dry mouth, and eyes that are itchy, red, and/or swollen. Carbonic anhydrase inhibitors (Trusopt, Azopt): This is another ...
As noted, timing your metformin dosage is crucial for mitigating the risk — and overall severity — of side effects. But what are those side effects exactly? The most common side effects of ...
Such placement may result from a multitude of considerations, including greater efficacy of other agents, socioeconomic considerations, availability issues, unpleasant side effects or similar issues relating to patient tolerance. Some experimental therapies might also be called drugs of last resort when administered following the failure of all ...
However, many are associated with an infamous side effect: weight gain. Luckily, some antidepressants are less likely to cause weight gain than others. In fact, there are even some antidepressants ...