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Last year, the FDA greenlighted the Astellas drug fezolinetant, sold as Veozah. It targets NK-3, the receptor that controls body temperature. It targets NK-3, the receptor that controls body ...
Fezolinetant, sold under the brand name Veozah among others, is a medication used for the treatment of hot flashes (vasomotor symptoms) due to menopause. [ 4 ] [ 10 ] It is a small-molecule , orally active , selective neurokinin-3 (NK 3 ) receptor antagonist which is under development for the treatment of sex hormone -related disorders .
The FDA just approved Veozah to treat hot flashes in menopausal women. Here’s how it works, why it’s a game-changer for certain women, and what it costs.
Elinzanetant (developmental code names BAY-3427080 GSK-1144814, NT-814) is an orally active small-molecule neurokinin/tachykinin NK 1 receptor and NK 3 receptor antagonist which is under development by Bayer, GlaxoSmithKline, and NeRRe Therapeutics for the treatment of hot flashes and "sex hormone disorders".
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Pavinetant (INN Tooltip International Nonproprietary Name, USAN Tooltip United States Adopted Name; developmental code names MLE-4901, AZD-4901, AZ-12472520, AZD-2624), is a small-molecule, orally active, selective neurokinin-3 (NK 3) receptor antagonist which was under development by AstraZeneca and Millendo Therapeutics for the treatment of hot flashes and polycystic ovary syndrome (PCOS).
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