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Human growth hormone (HGH) is a natural hormone your pituitary gland releases that promotes growth in children, helps maintain normal body structure in adults and plays a role in metabolism in both children and adults.
Growth hormone, peptide hormone secreted by the anterior lobe of the pituitary gland. It stimulates the growth of essentially all tissues of the body, including bone, and is vital for normal physical growth in children.
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development.
Human growth hormone is produced via the anterior pituitary of the brain in the acidophilic, somatotrophic cells. Its production is tightly regulated through several complex feedback mechanisms in response to stress, exercise, nutrition, sleep, and growth hormone itself.
Human growth hormone (HGH), also known as somatotropin, is a naturally occurring peptide hormone secreted by the pituitary gland. As its name implies, scientists originally found HGH to be responsible for growth regulation during childhood.
In adulthood, its main role is to regulate the metabolism. Pituitary synthesis and secretion of GH is stimulated by episodic hypothalamic secretion of GH releasing factor and inhibited by somatostatin. Insulin-like Growth Factor I (IGF-I) inhibits GH secretion by a negative loop at both hypothalamic and pituitary levels.
Growth Hormone Function. GH has direct metabolic effects on tissues by binding to cells, and has indirect effects by stimulating cells in the liver to produce insulin-like growth factors (IGFs or somatomedins). The main IGF is IGF-1.
Growth hormone levels are increased by sleep, stress, exercise and low glucose levels in the blood. They also increase around the time of puberty. Growth hormone release is lowered in pregnancy and if the brain senses high levels of growth hormone or insulin-like growth factors already in the blood.
Key Points. The growth hormone (GH)–insulin-like growth factor (IGF) axis consists of central neuro-anatomical, regulatory and genetic systems, and the peripheral intracellular GH signalling...
Growth hormone (GH) is produced by the pituitary somatotroph cells. GH production begins early in fetal life and continues throughout life, although at a progressively lower rate. The basic aspects of GH physiology will be reviewed here.