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Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. [1]
The malaria therapy (or malaria inoculation, [1] and sometimes malariotherapy [2]) is an archaic medical procedure of treating diseases using artificial injection of malaria parasites. [3] It is a type of pyrotherapy (or pyretotherapy) by which high fever is induced to stop or eliminate symptoms of certain diseases.
Artemisinin (/ ˌ ɑːr t ɪ ˈ m iː s ɪ n ɪ n /) and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to Plasmodium falciparum. [1] It was discovered in 1972 by Tu Youyou, who shared the 2015 Nobel Prize in Physiology or Medicine for her discovery. [2]
In the United States, the US Food and Drug Administration (FDA) limits the quinine content in tonic water to 83 ppm [8] (83 mg per liter), while the daily therapeutic dose of quinine is in the range of 500–1000 mg, [9] and 10 mg/kg every eight hours for effective malaria prevention (2,100 mg daily for a 70-kilogram (150 lb) adult). [10]
Malaria prophylaxis is the preventive treatment of malaria. Several malaria vaccines are under development. For pregnant women who are living in malaria endemic areas, routine malaria chemoprevention is recommended. It improves anemia and parasite level in the blood for the pregnant women and the birthweight in their infants. [1]
Malaria is a mosquito-borne infectious disease that affects vertebrates and Anopheles mosquitoes. [6] [7] [3] Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. [1] [8] In severe cases, it can cause jaundice, seizures, coma, or death.
Jesuits played a key role in the transfer of remedies from the New World. The traditional story connecting Cinchona species with malaria treatment was first recorded by Italian physician Sebastiano Bado in 1663. [10] [11] It tells of the wife of Luis Jerónimo de Cabrera, 4th Count of Chinchón and Viceroy of Peru, who fell ill in Lima with a ...
World Malaria Day 2023: “Time to deliver zero malaria: invest, innovate, implement” [15] World Malaria Day 2022: "Harness innovation to reduce the malaria disease burden and save lives." [16] World Malaria Day 2019-2020-2021: "Zero malaria starts with me" [17] World Malaria Day 2018: "Ready to beat malaria" World Malaria Day 2017: "LETS ...