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  2. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...

  3. Drug overdose - Wikipedia

    en.wikipedia.org/wiki/Drug_overdose

    Most overdoses occur when drugs are ingested in combination with alcohol. [32] Drug overdose was the leading cause of injury death in 2013. Among people 25 to 64 years old, drug overdose caused more deaths than motor vehicle traffic crashes. There were 43,982 drug overdose deaths in the United States in 2013.

  4. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    An appropriate drug policy relies on the assessment of drug-related public expenditure based on a classification system where costs are properly identified. Labelled drug-related expenditures are defined as the direct planned spending that reflects the voluntary engagement of the state in the field of illicit drugs.

  5. Addiction psychology - Wikipedia

    en.wikipedia.org/wiki/Addiction_psychology

    An issue with this theory is that most addictive drugs cause an individual to build up a tolerance and the effects of the drug will decrease as an individual's tolerance increases. This requires individuals to use a higher dosage of the substance which in many causes can cause adverse side effects. [34] Dopamine is correlated with increased ...

  6. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    Drug addiction, which belongs to the class of substance-related disorders, is a chronic and relapsing brain disorder that features drug seeking and drug abuse, despite their harmful effects. [31] This form of addiction changes brain circuitry such that the brain's reward system is compromised, [ 32 ] causing functional consequences for stress ...

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  8. Amphetamine dependence - Wikipedia

    en.wikipedia.org/wiki/Amphetamine_dependence

    When substituted amphetamines are used, drug tolerance develops rapidly. [8] Amphetamine dependence has shown to have the highest remission rate compared to cannabis, cocaine, and opioids. [ 9 ] Severe withdrawal associated with dependence from recreational substituted amphetamine use can be difficult for a user to cope with.

  9. Physical dependence - Wikipedia

    en.wikipedia.org/wiki/Physical_dependence

    It is debated whether the entire antipsychotic drug class causes true physical dependency, a subset, or if none do. [38] But, if discontinued too rapidly, it could cause an acute withdrawal syndrome. [39] When talking about illicit drugs rebound withdrawal, especially with stimulants, it is sometimes referred to as "coming down" or "crashing".