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Leukemia cutis is a localized symptom of a systemic underlying disease that requires systemic therapy tailored to the individual subtype of leukemia. Hematologic remission typically happens in tandem with a full or partial response to cutaneous infiltrations in the majority of individuals. [ 10 ]
Subleukemic leukemia, also known as leukemia subleukemic and aleukemic leukemia cutis, is a rare, cancerous blood disease characterized by the presence of abnormal or atypical white blood cells in the peripheral blood while the total white blood cell count is within the normal range. It can also be characterized by leukemic cells in the skin ...
These blood cells are not fully developed and are called blasts or leukemia cells. [2] Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. [2] These symptoms occur due to a lack of normal blood cells. [2] Diagnosis is typically made by blood tests or bone marrow biopsy. [2]
When a child has leukemia, the cells do not respond to the signals telling them when to stop and when to produce cells. The bone marrow becomes crowded, resulting in problems producing other blood cells. [4] [5] Common childhood leukemia signs and symptoms include excessive tiredness, easy bruising or bleeding, bone pain and paleness. [6]
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [1]
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. [1] Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. [1]
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Unexplained tiredness or fatigue: Unusual and persistent tiredness may point to underlying illness, including blood cell cancers like leukemia or lymphoma; Unexplained night sweats or fever: These may be signs of an immune system cancer. Fever in children rarely points to malignancy, but may merit evaluation. Local Symptoms