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The micropipette was invented and patented in 1960 by Dr. Heinrich Schnitger in Marburg, Germany. Afterwards, the co-founder of the biotechnology company Eppendorf, Dr. Heinrich Netheler, inherited the rights and initiated the global and general use of micropipettes in labs. In 1972, the adjustable micropipette was invented at the University of ...
Micropipette in action. Piston-driven air displacement pipettes are a type of micropipette, which are tools to handle volumes of liquid in the microliter scale. They are more commonly used in biology and biochemistry, and less commonly in chemistry; the equipment is susceptible to damage from many organic solvents.
The Micropipette developed by Heinrich Schnitger, which is often referred to as "Eppendorf pipette" in laboratory usage, [citation needed] counts today in various designs as standard almost every biomedical laboratories. For biologists, biochemists, biology laboratory technicians, medical-technical assistants and similar professions handling of ...
[10] [11] A set of two rings printed on the upper end of the pipette indicate that it is a "blow out" type and should be blown using a rubber bulb. Do not blow the solution out if the pipette has no rings on the upper end. [3]
There are two basic types of microinjection systems. The first is called a constant flow system and the second is called a pulsed flow system.In a constant flow system, which is relatively simple and inexpensive though clumsy and outdated, a constant flow of a sample is delivered from a micropipette and the amount of the sample which is injected is determined by how long the needle remains in ...
During a patch clamp recording, a hollow glass tube known as a micropipette or patch pipette filled with an electrolyte solution and a recording electrode connected to an amplifier is brought into contact with the membrane of an isolated cell. Another electrode is placed in a bath surrounding the cell or tissue as a reference ground electrode ...