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Stress can cause depression and depression-like symptoms through monoaminergic changes in several key brain regions as well as suppression in hippocampal neurogenesis. [118] This leads to alteration in emotion and cognition related brain regions as well as HPA axis dysfunction.
Psychological makeup can also play a role in vulnerability to depression. People who have low self-esteem, constantly view themselves and the world with pessimism, or are readily overwhelmed by stress, may be especially prone to depression. [33] Community surveys find that women are more likely than men to say they are under stress.
The survey also served to see the levels of anxiety, depression, and loneliness of the participants. The authors explain that: "Both loneliness and depressive symptoms declined in the experimental group". [35] Studies show that participants lowered their levels of depression and anxiety due to limiting their time on social media.
Depression is commonly attributed to a deficiency in monoamines, such as serotonin. The monoamine hypothesis of depression suggests that depression is primarily caused by a deficiency of several monoamines, namely serotonin, dopamine and norepinephrine. [2] This hypothesis is widely accepted due to its simplicity. [3]
"Fear of missing out" can lead to psychological stress at the idea of missing posted content by others while offline. The relationships between digital media use and mental health have been investigated by various researchers—predominantly psychologists, sociologists, anthropologists, and medical experts—especially since the mid-1990s, after the growth of the World Wide Web and rise of ...
[96] [97] Low self-esteem in particular can result in aggression, self-deprecating behavior, anxiety, and other mental disorders. [98] Being perceived as someone who does not "fit in" can result in bullying and other types of emotional abuse, [ 99 ] [ 100 ] which can lead to the victim experiencing depression, anger, and loneliness.
Instead, dopamine is more closely related to the drive for hunger and thirst. Although the lack of dopamine resulted in adipsia in these rats, low levels of dopamine do not necessarily cause adipsia. [9] The nigrostriatal pathway (highlighted in blue) is crucial for dopamine production and transmission. Location of the hypothalamus in the brain.
[7] Research also supports that atypical depression tends to have an earlier onset, with teenagers and young adults more likely to exhibit atypical depression than older patients. [2] Patients with atypical depression have shown to have higher rates of neglect and abuse in their childhood as well as alcohol and drug disorders in their family. [10]