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  2. Acetylcysteine - Wikipedia

    en.wikipedia.org/wiki/Acetylcysteine

    Acetylcysteine is extensively liver metabolized, CYP450 minimal, urine excretion is 22–30% with a half-life of 5.6 hours in adults and 11 hours in newborns. [medical citation needed] Acetylcysteine is the N-acetyl derivative of the amino acid L-cysteine, and is a precursor in the formation of the antioxidant glutathione in the body.

  3. Acetylcholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Acetylcholinesterase_inhibitor

    Acetylcholine Acetylcholinesterase Acetylcholinesterase inhibition. Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, [1] inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, [2] thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ...

  4. Thiamphenicol glycinate acetylcysteine - Wikipedia

    en.wikipedia.org/wiki/Thiamphenicol_glycinate...

    TGA works by releasing thiamphenicol glycinate ester (TAFGE) and N-acetylcysteine (NAC) upon contact with tissue esterases. [1] Esterases are enzymes that break down esters into an acid and an alcohol in a chemical reaction with water called hydrolysis. [6] Such reaction is needed to split TGA into its active components.

  5. Drug metabolism - Wikipedia

    en.wikipedia.org/wiki/Drug_metabolism

    Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems. More generally, xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as any drug ...

  6. Protein acetylation - Wikipedia

    en.wikipedia.org/wiki/Protein_acetylation

    Signal transducer and activator of transcription 3 is a transcription factor that is phosphorylated by receptor associated kinases, for example, Janus-family tyrosine kinases, and translocate to nucleus. STAT3 regulates several genes in response to growth factors and cytokines and play an important role in cell growth.

  7. Medical prescription - Wikipedia

    en.wikipedia.org/wiki/Medical_prescription

    [citation needed] Predating modern legal definitions of a prescription, a prescription traditionally is composed of four parts: a superscription, inscription, subscription, and signature. [48] The superscription section contains the date of the prescription and patient information (name, address, age, etc.). The symbol "℞" separates the ...

  8. NAPQI - Wikipedia

    en.wikipedia.org/wiki/NAPQI

    NAPQI, also known as NAPBQI or N-acetyl-p-benzoquinone imine, is a toxic byproduct produced during the xenobiotic metabolism of the analgesic paracetamol (acetaminophen). [1] It is normally produced only in small amounts, and then almost immediately detoxified in the liver.

  9. Adenylyl cyclase - Wikipedia

    en.wikipedia.org/wiki/Adenylyl_cyclase

    It catalyzes the following reaction: ATP = 3′,5′-cyclic AMP + diphosphate. It has key regulatory roles in essentially all cells. [2] It is the most polyphyletic known enzyme: six distinct classes have been described, all catalyzing the same reaction but representing unrelated gene families with no known sequence or structural homology. [3]