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In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase [1] whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase (EC 2.7.11.11). PKA has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.
pKa values for acetic, chloroacetic, dichloroacetic and trichloroacetic acids. Inductive effects and mesomeric effects affect the pK a values. A simple example is provided by the effect of replacing the hydrogen atoms in acetic acid by the more electronegative chlorine atom.
In computational biology, protein pK a calculations are used to estimate the pK a values of amino acids as they exist within proteins.These calculations complement the pK a values reported for amino acids in their free state, and are used frequently within the fields of molecular modeling, structural bioinformatics, and computational biology.
In chemistry, biochemistry, and pharmacology, a dissociation constant (K D) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.
Dihydroxyacetone kinase in complex with a non-hydrolyzable ATP analog (AMP-PNP). Coordinates from PDB ID:1UN9. [1]In biochemistry, a kinase (/ ˈ k aɪ n eɪ s, ˈ k ɪ n eɪ s,-eɪ z /) [2] is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.
In condensed-matter physics, a primary knock-on atom (PKA) is an atom that is displaced from its lattice site by irradiation; it is, by definition, the first atom that an incident particle encounters in the target.
Physics – negentropy, stochastic processes, and the development of new physical techniques and instrumentation as well as their application. Quantum biology – The field of quantum biology applies quantum mechanics to biological objects and problems. Decohered isomers to yield time-dependent base substitutions. These studies imply ...
18821 Ensembl ENSG00000198523 ENSMUSG00000038583 UniProt P26678 P61014 RefSeq (mRNA) NM_002667 NM_001141927 NM_023129 RefSeq (protein) NP_002658 NP_001135399 NP_075618 Location (UCSC) Chr 6: 118.55 – 118.56 Mb Chr 10: 53.21 – 53.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Phospholamban, also known as PLN or PLB, is a micropeptide protein that in humans is encoded by the ...