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2003: Excedrin Tension Headache contains 500 mg acetaminophen, and 65 mg caffeine. 2005: Excedrin Sinus Headache contains 325 mg acetaminophen and 5 mg phenylephrine HCl as a decongestant. 2007: Excedrin Back and Body – a dual-ingredient formula claiming that it "works two ways—as a pain reliever and a pain blocker right where it hurts".
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According to this classification, migraine is a primary headache disorder along with tension-type headaches and cluster headaches, among others. [118] Migraine is divided into six subclasses (some of which include further subdivisions): [119] Migraine without aura, or "common migraine", involves migraine headaches that are not accompanied by aura.
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The combination was first introduced as the name Trigesic, as the formula of 125 mg paracetamol, 230 mg aspirin, and 30 mg caffeine, in July 1950 by Squibb, which is now Bristol Myers Squibb, but was recalled in the following year due to several reports that the drug might cause blood dyscrasia. [5]
Common over-the-counter medicines that can cause headaches when overused include Excedrin Migraine, Cafergot, and Advil. [11] [12] Dietary and medicinal caffeine consumption appears to be a modest risk factor for chronic daily headache onset, regardless of headache type. [13] [14] A lifelong history of headaches is a major risk factor for MOH. [15]
Paracetamol, [a] or acetaminophen, [b] is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [13] [14] [15] It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol.
Nitrite is found in dynamite, heart medicine and it is a chemical used to preserve meat (ergo these being known as "nitrite" or "hot dog" headaches). [2] Eating foods prepared with monosodium glutamate (MSG) may thus result in headache. Acetaldehyde from alcohol may also cause a headache either acutely or after a number of hours .