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The five main classes in the Vaughan Williams classification of antiarrhythmic agents are: Class I agents interfere with the sodium (Na +) channel. Class II agents are anti-sympathetic nervous system agents. Most agents in this class are beta blockers. Class III agents affect potassium (K +) efflux. Class IV agents affect calcium channels and ...
Class of antihypertensives that bind to and inhibit the angiotensin II receptor type 1 and thereby block the arteriolar contraction and sodium retention effects of renin–angiotensin system. Azilsartan medoxomil; Candesartan; Eprosartan; Fimasartan; Irbesartan; Losartan; Olmesartan; Telmisartan; Valsartan
ATC code C01 Cardiac therapy is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] Subgroup C01 is part of the anatomical group C Cardiovascular system. [4]
Pages in category "Antiarrhythmic agents" The following 59 pages are in this category, out of 59 total. This list may not reflect recent changes. ...
ATC code C Cardiovascular system is a section of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] [4]
This contrasts with (ordinary) use dependence, where the efficacy of the drug is increased after repeated use of the tissue. Reverse use dependence is relevant for potassium channel blockers used as class III antiarrhythmics. Reverse use dependent drugs that slow heart rate (such as quinidine) can be less effective at high heart rates. [11]
Antiarrhythmics are broad class of drugs that are used treat heart rhythm irregularities. [16] Utilizing the Vaughan-Williams (VW) system, antiarrhymic drugs are classified into four main classes based on their mechanism of action. Class I antiarrhymics lead to blockage of sodium channels. Class II antiarrhymatics are beta-adrenoceptor blockers.
Procainamide (PCA) is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias. It is a sodium channel blocker of cardiomyocytes; thus it is classified by the Vaughan Williams classification system as class Ia. In addition to blocking the I Na current, it inhibits the I Kr rectifier K+ current. [1]