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  2. Meningioma - Wikipedia

    en.wikipedia.org/wiki/Meningioma

    Meningioma, also known as meningeal tumor, is typically a slow-growing tumor that forms from the meninges, the membranous layers surrounding the brain and spinal cord. [1] Symptoms depend on the location and occur as a result of the tumor pressing on nearby tissue.

  3. Central nervous system tumor - Wikipedia

    en.wikipedia.org/wiki/Central_nervous_system_tumor

    The causes of CNS tumors are poorly understood. A few risk factors are known, including radiation exposure, genetic disorder, a family history of CNS tumors, immunodeficiency, stress and a history of previous cancers. As with all cancers, the risk of developing a CNS tumor increases with age. [10]

  4. Optic nerve sheath meningioma - Wikipedia

    en.wikipedia.org/wiki/Optic_nerve_sheath_meningioma

    This causes loss of vision in the affected eye. [1] Rarely, it may affect both eyes at the same time. [2] It is typically a slow growing tumor, and has never been reported to cause death. However, there is concern that the tumor can grow into the brain and cause other types of neurological damage. In some patients, the tumor grows so slowly ...

  5. Pia mater - Wikipedia

    en.wikipedia.org/wiki/Pia_mater

    Most meningiomas grow from the arachnoid mater inward applying pressure on the pia mater and therefore the brain or spinal cord. While meningiomas make up 20% of primary brain tumors and 12% of spinal cord tumors, 90% of these tumors are benign. Meningiomas tend to grow slowly and therefore symptoms may arise years after initial tumor formation.

  6. Cerebral edema - Wikipedia

    en.wikipedia.org/wiki/Cerebral_edema

    Cerebral edema is commonly seen in a variety of brain injuries including ischemic stroke, subarachnoid hemorrhage, traumatic brain injury, subdural, epidural, or intracerebral hematoma, hydrocephalus, brain cancer, brain infections, low blood sodium levels, high altitude, and acute liver failure.

  7. Diffuse axonal injury - Wikipedia

    en.wikipedia.org/wiki/Diffuse_axonal_injury

    High levels of intracellular Ca 2+, the major cause of post-injury cell damage, [30] destroy mitochondria, [11] and trigger phospholipases and proteolytic enzymes that damage Na+ channels and degrade or alter the cytoskeleton and the axoplasm. [31] [26] Excess Ca 2+ can also lead to damage to the blood–brain barrier and swelling of the brain ...

  8. Leptomeningeal cancer - Wikipedia

    en.wikipedia.org/wiki/Leptomeningeal_cancer

    The treatment is done to reduce pressure on the brain caused by any cerebrospinal fluid buildup and to reduce the number of cancer cells causing the pressure. For the best care, patients should see a physician who regularly treats leptomeningeal cancer and is most up-to-date on medicines that penetrate the blood-brain barrier, how to treat the ...

  9. Blood–brain barrier - Wikipedia

    en.wikipedia.org/wiki/Blood–brain_barrier

    The blood–brain barrier is formed by the brain capillary endothelium and excludes from the brain 100% of large-molecule neurotherapeutics and more than 98% of all small-molecule drugs. [28] Overcoming the difficulty of delivering therapeutic agents to specific regions of the brain presents a major challenge to treatment of most brain disorders.

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