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Concentric hypertrophy is a hypertrophic growth of a hollow organ without overall enlargement, [1] in which the walls of the organ are thickened and its capacity or volume is diminished. Sarcomeres are added in parallel, as for example occurs in hypertrophic cardiomyopathy .
Concentric hypertrophy results from various stressors to the heart including hypertension, congenital heart defects (such as Tetralogy of Fallot), valvular defects (aortic coarction or stenosis), and primary defects of the myocardium which directly cause hypertrophy (hypertrophic cardiomyopathy). The underlying commonality in these disease ...
Ventricular remodeling may include ventricular hypertrophy, ventricular dilation, cardiomegaly, and other changes. It is an aspect of cardiomyopathy, of which there are many types. Concentric hypertrophy is due to pressure overload, while eccentric hypertrophy is due to volume overload. [6]
Dr. Davis emphasizes that valve damage is not only caused by poor dietary habits, explaining, “Diet is often talked about in connection to heart disease, but valve damage has different causes.
The concentric hypertrophy is due to the increased left ventricular pressure overload associated with AI, while the eccentric hypertrophy is due to volume overload caused by the regurgitant fraction. [15] Physiologically, in individuals with a normally functioning aortic valve, the valve is only open when the pressure in the left ventricle is ...
This means that as the heart muscle wall enlarges, it crowds into the ventricular chamber space, resulting in less room for blood, meaning that in addition to contributing to systolic dysfunction, hypertension also can cause diastolic heart failure. Concentric hypertrophy leading to diastolic failure can also be caused by aortic stenosis, which ...