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A cardiac stress test is a cardiological examination that evaluates the cardiovascular system's response to external stress within a controlled clinical setting. This stress response can be induced through physical exercise (usually a treadmill) or intravenous pharmacological stimulation of heart rate.
Gated SPECT is a nuclear medicine imaging technique, typically for the heart in myocardial perfusion imagery. [1] An electrocardiogram (ECG) guides the image acquisition, and the resulting set of single-photon emission computed tomography (SPECT) images shows the heart as it contracts over the interval from one R wave to the next.
Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (). [1]It evaluates many heart conditions, such as coronary artery disease (CAD), [2] hypertrophic cardiomyopathy and heart wall motion abnormalities.
Regadenoson, sold under the brand name Lexiscan among others, is an A 2A adenosine receptor agonist that is a coronary vasodilator that is commonly used in pharmacologic stress testing. It produces hyperemia quickly and maintains it for a duration that is useful for radionuclide myocardial perfusion imaging . [ 1 ]
Single-photon emission computed tomography (SPECT, or less commonly, SPET) is a nuclear medicine tomographic imaging technique using gamma rays. [1] It is very similar to conventional nuclear medicine planar imaging using a gamma camera (that is, scintigraphy), [2] but is able to provide true 3D information. This information is typically ...
In a stress MUGA, patients with coronary artery disease may exhibit a decrease in ejection fraction. For a patient that has had a heart attack, or is suspected of having another disease that affects the heart muscle, this scan can help pinpoint the position in the heart that has sustained damage as well as assess the degree of damage.
In order to obtain spatial information about the gamma-ray emissions from an imaging subject (e.g. a person's heart muscle cells which have absorbed an intravenous injected radioactive, usually thallium-201 or technetium-99m, medicinal imaging agent) a method of correlating the detected photons with their point of origin is required.
The stress test can result in three outcomes: Pass, Partly Pass and Fail, based on the comparison of the quantified risks to acceptable risk exposure levels and a penalty system. Phase 3: Decision, during which the results of the stress test are analyzed according to the goal and objectives defined in Phase 1. Critical events (events that most ...