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A lung nodule or pulmonary nodule is a relatively small focal density in the lung. A solitary pulmonary nodule (SPN) or coin lesion, [1] is a mass in the lung smaller than three centimeters in diameter. A pulmonary micronodule has a diameter of less than three millimetres. [2] There may also be multiple nodules.
[5] [6] The regional lymph nodes are normally removed as these may show evidence of spread. Bronchoscopy is not usually useful as these lesions tend to lie in the perifery of the lung. Fine needle aspirates may be not be sufficient to make the diagnosis. [7] [8] Blood tests are normal. CT shows a solitary nodule with may have some calcium present.
Histoplasmosis can also be diagnosed by a test for antibodies against Histoplasma in the blood. Histoplasma skin tests indicate whether persons have been exposed, but do not indicate whether they have the disease. [4] Formal histoplasmosis diagnoses are often confirmed only by culturing the fungus directly. [6]
Pulmonary tuberculomas are among the most common benign nodules, with 5%-24% of all resected nodules being of tuberculous origin. [21] In areas of lower prevalence, such as the United States, they are most commonly seen in the setting of an acquired immunodeficiency . [ 23 ]
A lung nodule is a discrete opacity in the lung which may be caused by: Neoplasm: benign or malignant; Granuloma: tuberculosis; Infection: round pneumonia; Vascular: infarct, varix, granulomatosis with polyangiitis, rheumatoid arthritis; There are a number of features that are helpful in suggesting the diagnosis: rate of growth
The calcified nodule can be within the lung, hila, or mediastinum. The borders must be sharp, distinct, and well defined. This was considered a Class B3 TB in the past; however, Class B3 has been omitted from the classification scheme because it has not been found to be associated with active TB.
A focal lung pneumatosis is an enclosed pocket of air or gas in the lung and includes blebs, bullae, pulmonary cysts, and lung cavities. Blebs and bullae can be classified by their wall thickness. [1] A bleb has a wall thickness of less than 1 mm. [2] By radiology definition, it is up to 1 cm in total size. [3]
Pulmonary laceration is usually accompanied by hemoptysis (coughing up blood or of blood-stained sputum). [12] Thoracoscopy may be used in both diagnosis and treatment of pulmonary laceration. [8] A healing laceration may resemble a lung nodule on radiographs, but unlike pulmonary nodules, lacerations decrease in size over time on radiographs. [4]