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People who rely on Qualaquin, also known as quinine sulfate, to combat their nighttime leg cramps are putting their lives at risk, warned the Food and Drug Administration. The federal agency ...
Quinine is no longer recommended for treatment of nocturnal leg cramps due to potential fatal hypersensitivity reactions and thrombocytopenia. Arrhythmias , cinchonism , and hemolytic uremic syndrome can also occur at higher dosages.
Quinine is a medication used to treat malaria and babesiosis. [5] This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available. [5] [6] While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. [5]
Until about 2010, [11] quinine was often recommended as a relief for leg cramps, although medical research suggested some care was needed in monitoring doses. [12] Because of quinine's risks, the FDA cautions consumers against using "off-label" quinine drugs to treat leg cramps. [13]
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The causes of leg cramps at night can range from nutrient deficiency to tough workouts. Here, experts break down how to prevent and get rid of leg cramps.
Generally, muscle relaxants or quinine can help with cramps and is warranted when they become troublesome. But these medication cause their relaxing effect in both groups by moderating their tone. The cause of disproportionate intermittent contractions of either flexors or extensors or the cause of cramps is unknown.
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