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Crawley is at the origin of several widely employed tests used to evaluate, for example, anxiety-related and social behavior in rodents, especially mice. Early in her career, she developed the light-dark mouse exploration test, and showed that it is a valid test for anxiety-like behaviors.
[12] [13] Social interaction is measured by how the mouse interacts with a stranger mouse introduced in the opposite side of a test box. [14] Researchers from the University of Florida have used deer mice to study restricted and repetitive behavior such as compulsive grooming, and how these behaviors may be caused by specific gene mutations. [15]
Behavioral sink" is a term invented by ethologist John B. Calhoun to describe a collapse in behavior that can result from overpopulation. The term and concept derive from a series of over-population experiments Calhoun conducted on Norway rats between 1958 and 1962. [ 1 ]
[2] [3] There are up to 40 tests in SHIRPA, across three screens of increasing complexity and specialization. [2] The first describes the behavior of the mouse subject by observation. The second involves a more thorough behavioral assessment and includes pathological analysis.
Rather, it has become a widely accepted belief among behavior geneticists that the superiority of the bright rats may have been confined to Tryon’s specific test; thus, it is not necessarily due to a difference in learning capacity between the two groups of rats.
The test was first developed by Dr. Carol Barnes in 1979. [1] The test subjects are usually rodents such as mice or lab rats , which either serve as a control or may have some genetic variable or deficiency present in them which will cause them to react to the maze differently.
Conditioned place preference (CPP) is a form of Pavlovian conditioning used to measure the motivational effects of objects or experiences. [1] This motivation comes from the pleasurable aspect of the experience, so that the brain can be reminded of the context that surrounded the "encounter". [2]
The hole-board test (HBT) is an experimental method used in scientific research to measure anxiety, stress, neophilia and emotionality in animals. [ 1 ] [ 2 ] [ 3 ] Because of its ability to measure multiple behaviors it is a popular test in behavioral pharmacology , but the results are controversial.