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  2. H5N1 genetic structure - Wikipedia

    en.wikipedia.org/wiki/H5N1_genetic_structure

    The genetic structure of H5N1, a highly pathogenic avian influenza virus (influenza A virus subtype H5N1), is characterized by a segmented RNA genome consisting of eight gene segments that encode for various viral proteins essential for replication, host adaptation, and immune evasion.

  3. Influenza A virus - Wikipedia

    en.wikipedia.org/wiki/Influenza_A_virus

    Influenza viruses have a relatively high mutation rate that is characteristic of RNA viruses. [48] The segmentation of the influenza A virus genome facilitates genetic recombination by segment reassortment in hosts who become infected with two different strains of influenza viruses at the same time.

  4. Orthomyxoviridae - Wikipedia

    en.wikipedia.org/wiki/Orthomyxoviridae

    Influenza A virus structure. The influenzavirus virion is pleomorphic; the viral envelope can occur in spherical and filamentous forms. In general, the virus's morphology is ellipsoidal with particles 100–120 nm in diameter, or filamentous with particles 80–100 nm in diameter and up to 20 μm long. [5]

  5. Influenza - Wikipedia

    en.wikipedia.org/wiki/Influenza

    Influenza viruses have a negative-sense, single-stranded RNA genome that is segmented. The negative sense of the genome means it can be used as a template to synthesize messenger RNA (mRNA). [10] Influenza A virus and influenza B virus have eight genome segments that encode 10 major proteins.

  6. Influenza B virus - Wikipedia

    en.wikipedia.org/wiki/Influenza_B_virus

    The influenza B virus genome is 14,548 nucleotides long and consists of eight segments of linear negative-sense, single-stranded RNA.The multipartite genome is encapsidated, each segment in a separate nucleocapsid, and the nucleocapsids are surrounded by one envelope.

  7. Influenza Research Database - Wikipedia

    en.wikipedia.org/wiki/Influenza_Research_Database

    Sequence Variation Analysis (SNP): pre-computed sequence variation analysis in all IRD sequences; also allows users to calculate the extent of sequence variation in user-specified sequences PCR Primers/Probes: provides a repository of commonly used primers for influenza virus identification, and calculates the polymorphisms of all related IRD ...

  8. Hemagglutinin (influenza) - Wikipedia

    en.wikipedia.org/wiki/Hemagglutinin_(influenza)

    Influenza hemagglutinin (HA) or haemagglutinin [p] (British English) is a homotrimeric glycoprotein found on the surface of influenza viruses and is integral to its infectivity. Hemagglutinin is a class I fusion protein, [1] [2] having multifunctional activity as both an attachment factor and membrane fusion protein.

  9. Influenza Genome Sequencing Project - Wikipedia

    en.wikipedia.org/wiki/Influenza_Genome...

    The project makes all sequence data publicly available through GenBank, an international, NIH-funded, searchable online database.This research helps to provide international researchers with the information needed to develop new vaccines, therapies and diagnostics, as well as improve understanding of the overall molecular evolution of Influenza and other genetic factors that determine their ...