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The cause of depression is believed to be due to a combined effect of genetic and environmental factors. [11] Other medical conditions, for example hypothyroidism, may cause people to experience similar symptoms as a major depressive episode. [20]
Depressed individuals have a shorter life expectancy than those without depression, in part because people who are depressed are at risk of dying of suicide. [262] About 50% of people who die of suicide have a mood disorder such as major depression, and the risk is especially high if a person has a marked sense of hopelessness or has both ...
An estimated 4.4 percent of the global population has depression, according to a report released by the UN World Health Organization (WHO), which shows an 18 percent increase in the number of people living with depression between 2005 and 2015. [66] [67] [68] Depression is a major mental-health cause of disease burden.
In many cases, suicide is an attempt to escape a situation that causes unbearable suffering. A majority of those that die by suicide suffer from depression, alcoholism or other mental health problems such as bipolar disorder. [1] Some that die by suicide have organic disorders such as brain trauma and epilepsy. [2]
The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
About 50% of people who die of suicide have a mood disorder such as major depression. [182] [183] Sleep and diet may play a role in depression (major depressive disorder), and interventions in these areas may be an effective add-on to conventional methods. [184] Vitamin B 2, B 6 and B 12 deficiency may cause depression in females. [185]
Of the roughly 150,000 people who die each day across the globe, about two thirds—100,000 per day—die of age-related causes. [79] In industrialized nations, the proportion is higher, reaching 90%.
Suicide is often committed in response to a cause of depression, such as the cessation of a romantic relationship, serious illness or injury (like the loss of a limb or blindness), the death of a loved one, financial problems or poverty, guilt or fear of getting caught for something the person did, drug abuse, old age, concerns with gender ...