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Because some adverse effects may only emerge during chronic use of methylphenidate, a constant watch for adverse effects is recommended. A 2018 Cochrane review found that methylphenidate might be associated with serious side effects such as heart problems, psychosis, and death. The certainty of the evidence was stated as very low.
The long-term effects on mental health disorders in later life of chronic use of methylphenidate is unknown. A 2009 FDA review of 49 clinical trials found that approximately 1.5% of children in clinical trials of medications for ADHD had experienced signs or symptoms of psychosis or mania.
The word methylphenidate is a portmanteau of the chemical name, Methyl -2- phen yl-2- (p i peri d in-2-yl) acet ate . The name "Ritalin" derives from Marguerite "Rita" Panizzon, the wife of Leandro Panizzon, who first synthesized the drug in 1944. Rita was the first person to take methylphenidate, and described its effects to her husband.
Solriamfetol, sold under the brand name Sunosi, is a wakefulness-promoting medication used in the treatment of excessive sleepiness related to narcolepsy and sleep apnea. [3] [5] [6] It is taken by mouth. [3] Common side effects of solriamfetol include headache, nausea, anxiety, and trouble sleeping. [3]
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