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A gout flare comes on suddenly, and symptoms are often intense. This will most commonly happen at night. Gout in foot joints is most common, with gout often affecting the big toe joint.
Gout most often affects middle-aged and older men. In fact, men are three to 10 times more likely to have gout than women. However, younger men and women of all ages can have gout.
Rates of gout approximately doubled between 1990 and 2010. [17] This rise is believed to be due to increasing life expectancy, changes in diet and an increase in diseases associated with gout, such as metabolic syndrome and high blood pressure. [25] Factors that influence rates of gout include age, race, and the season of the year.
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Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [4] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...