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Benzalkonium chloride is a frequently used preservative in eye drops. Typical concentrations range from 0.004% to 0.01%. [17] Stronger concentrations can be caustic [18] and cause irreversible damage to the corneal endothelium. [19] Avoiding the use of benzalkonium chloride solutions while contact lenses are in place is discussed in the literature.
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Benzalkonium chloride solution (Cloruro de benzalconio, tintura), distributed by Bayer de México under the name "merthiolate" Benzalkonium chloride and red dye solution, marketed by DLC Laboratories, Inc. of Paramount, California, as a mercury-free skin antiseptic under the name "Merthiolate" (brand name: De La Cruz)
Preservative-free eye drops are found in single vials. However, single unit-dose artificial tears without preservatives are more expensive than bottled artificial tears with preservatives. [9] Some patients confuse over the counter drops that contain tetrahydrozoline (i.e. Visine®), a vasoconstrictor, with artificial tears. [11]