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Macular hard drusen in the right eye. 65-year-old diabetic woman. Drusen, from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a few small ("hard") drusen is normal with ...
The optic nerve is a cable connection that transmits images from the retina to the brain.It consists of over one million retinal ganglion cell axons.The optic nerve head, or optic disc is the anterior end of the nerve that is in the eye and hence is visible with an ophthalmoscope.
Uveitis is an ophthalmic emergency that requires urgent control of the inflammation to prevent vision loss. Treatment typically involves the use of topical eye drop steroids, intravitreal injection, newer biologics, and treating any underlying disease.
The majority of people over age 60 have drusen with no adverse effects. The risk of developing symptoms is higher when the drusen are large and numerous, and associated with the disturbance in the pigmented cell layer under the macula. Large and soft drusen are thought to be related to elevated cholesterol deposits. [citation needed]
At an eye exam, the pupils may not respond normally to light. Some affected individuals have cloudy eyes , and irregularly shaped corneas (keratoconus). [9] Retinal exams typically look normal, especially in the young, though retinal abnormalities can appear later in life. [10] Aside from eye problems, children with LCA are typically healthy.
Bruch's membrane thickens with age, slowing the transport of metabolites. This may lead to the formation of drusen in age-related macular degeneration. [4] There is also a buildup of deposits (Basal Linear Deposits or BLinD and Basal Lamellar Deposits BLamD) on and within the membrane, primarily consisting of phospholipids.