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Lovastatin is contraindicated during pregnancy (Pregnancy Category X); it may cause birth defects such as skeletal deformities or learning disabilities. Owing to its potential to disrupt infant lipid metabolism, lovastatin should not be taken while breastfeeding. [11] Patients with liver disease should not take lovastatin. [12]
Simvastatin is contraindicated with pregnancy, breastfeeding, and liver disease. [16] Pregnancy must be avoided while on simvastatin due to potentially severe birth defects. Patients cannot breastfeed while on simvastatin due to potentially disrupting the infant's lipid metabolism. [17]
Rosuvastatin has multiple contraindications, including hypersensitivity to rosuvastatin or any component of the formulation, active liver disease, elevation of serum transaminases, pregnancy, or breastfeeding. [4] Rosuvastatin is not prescribed nor used while pregnant, as it can cause serious harm to the fetus. [4]
Breastfeeding: Small amounts of other statin medications have been found to pass into breast milk, although atorvastatin has not been studied specifically. [4] Due to risk of disrupting a breastfeeding infant's metabolism of lipids, atorvastatin is not regarded as compatible with breastfeeding. [54]
Mercury is especially harmful to pregnant and breastfeeding women and children, but rather than avoiding fish, eating lower mercury fish at least twice per week is recommended.
For people ages 40 to 60, 35–40% died of heart-related disease. To find out whether statin use could help lower death risk from heart disease among older adults in these age groups, the authors ...
It's definitely not a good idea for anyone with a history of disordered eating or diabetes and those who are pregnant or breastfeeding—even if weight loss is recommended, says Dana White, RD, a ...
Serious side effects may include rhabdomyolysis, liver problems, and diabetes. [5] Use during pregnancy may harm the fetus. [5] Like all statins, pravastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver that plays a role in producing cholesterol. [5] Pravastatin was patented in 1980 and approved for medical use in 1989. [6]