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  2. Patient Reported Outcome Indices for Multiple Sclerosis

    en.wikipedia.org/wiki/Patient_Reported_Outcome...

    The Patient Reported Outcome Indices for Multiple Sclerosis (PRIMUS) is a disease specific patient-reported outcome questionnaire which measures the quality of life (QoL) of patients with multiple sclerosis. [1] The measure contains an assessment of quality of life, activity limitations and symptoms.

  3. Expanded Disability Status Scale - Wikipedia

    en.wikipedia.org/wiki/Expanded_Disability_Status...

    The Kurtzke Expanded Disability Status Scale (EDSS) is a method of quantifying disability in multiple sclerosis. [1] [2] The scale has been developed by John F. Kurtzke. [1] The EDSS is based on a neurological examination by a clinician. However, a number of versions have been developed which enable patient self-administration. [3]

  4. McDonald criteria - Wikipedia

    en.wikipedia.org/wiki/McDonald_criteria

    The McDonald criteria are diagnostic criteria for multiple sclerosis (MS). These criteria are named after neurologist W. Ian McDonald who directed an international panel in association with the National Multiple Sclerosis Society (NMSS) of America and recommended revised diagnostic criteria for MS in April 2001.

  5. Management of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Management_of_multiple...

    In March 2017, ocrelizumab was approved in the United States for the treatment of primary progressive multiple sclerosis in adults. [22] [42] It is also used for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. [42]

  6. Diagnosis of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Diagnosis_of_multiple_sclerosis

    Unusual types of MS have been described; these include Devic's disease, Balo concentric sclerosis, Schilder's diffuse sclerosis, and Marburg multiple sclerosis. There is debate on whether they are MS variants or different diseases. [31] Multiple sclerosis behaves differently in children, taking more time to reach the progressive stage. [5]

  7. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis. Multiple sclerosis is an autoimmune disease, primarily mediated by T-cells. [15] The three main characteristics of MS are the formation of lesions in the central nervous system (also called plaques), inflammation, and the destruction of myelin sheaths of neurons.

  8. Medical guideline - Wikipedia

    en.wikipedia.org/wiki/Medical_guideline

    Plates vi & vii of the Edwin Smith Papyrus (around the 17th century BC), among the earliest medical guidelines. A medical guideline (also called a clinical guideline, standard treatment guideline, or clinical practice guideline) is a document with the aim of guiding decisions and criteria regarding diagnosis, management, and treatment in specific areas of healthcare.

  9. Multiple sclerosis functional composite - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis...

    It was developed over two years from 1994 to 1996 by the National Multiple Sclerosis Society. [1] [2] MSFC was developed to improve the standard measure of MS disability for clinical trials and to create a multidimensional metric of overall MS clinical status. The evaluation includes a three-part performance scale: