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Subcutaneous injection sites. Commonly used injection sites include: [3]: 723 The outer area of the upper arm. The abdomen, avoiding a 2-inch circle around the navel. The front of the thigh, between 4 inches from the top of the thigh and 4 inches above the knee. The upper back. The upper area of the buttock, just behind the hip bone.
For certain substances, administration via an ID route can result in a faster systemic uptake compared with subcutaneous injections, [1] leading to a stronger immune response to vaccinations, immunology [clarification needed] and novel cancer treatments, and faster drug uptake. [2]
Subcutaneous (under the skin). [22] This generally takes the form of subcutaneous injection, e.g. with insulin. Skin popping is a slang term that includes subcutaneous injection, and is usually used in association with recreational drugs. In addition to injection, it is also possible to slowly infuse fluids subcutaneously in the form of ...
Subcutaneous: Subcutaneous injections are given at a 45-degree angle, usually in the thigh (for babies under the age of 12 months) or upper-outer triceps area for people over 12 months. The MMR ...
For many biologics (e.g., monoclonal antibodies), injection site reactions are the most common adverse effect of the drug, and have been reported to have an incidence rate of 0.5–40%. [ 2 ] In trials of subcutaneous administration of oligonucleotides , between 22 and 100% of subjects developed reactions depending on the oligonucleotide.
It is usually a depot injection, either subcutaneous or intradermal, and not an intramuscular injection. After deposition, the drug then diffuses slowly from the depot into the capillary networks, where it enters circulation. Skin popping is distinct from intravenous injection in that the latter deposits the drug directly into the bloodstream ...
The desired injection site and the skin profile at the injection site will determine what needle length is appropriate for a person to use. [23] For products with included needles, such as epinephrine pens, different brands may have different included needle lengths, which must be taken into account.
Charles Hunter, a London surgeon, is credited with the coining of the term "hypodermic" to describe subcutaneous injection in 1858. The name originates from two Greek words: hypo, "under", and derma, "skin". Furthermore, Hunter is credited with acknowledging the systemic effects of injection after noticing that a patient's pain was alleviated ...