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Subacute cutaneous lupus erythematosus (SCLE ) is a clinically distinct subset of cases of lupus erythematosus that is most often present in white women aged 15 to 40, consisting of skin lesions that are scaly and evolve as poly-cyclic annular lesions or plaques similar to those of plaque psoriasis. [1]
Clinical criteria: Individuals exhibiting 1) lesions that occur in acute cutaneous lupus erythematosus such as a malar rash, toxic epidermal necrolysis, bullae, (i.e., large blisters containing serous fluid), maculopapular rashes, photosensitive lupus-like rashes (in individuals who do not have dermatomyositis), or subacute cutaneous lupus ...
Lupus is Latin for "wolf", [154] [10] and in Medieval Latin was also used to refer to a disease of the skin, [155] and "erythematosus" is derived from ἐρύθημα, Ancient Greek for "redness of the skin". All explanations originate with the reddish, butterfly-shaped malar rash that the disease classically exhibits across the nose and cheeks.
Neonatal lupus erythematosus is an autoimmune disease in an infant born to a mother with anti-Ro/SSA and with or without anti-La/SSB antibodies. [1] [2] The disease most commonly presents with a diffuse/periorbital rash resembling subacute cutaneous lupus erythematosus and can have systemic abnormalities such as complete heart block or hepatosplenomegaly. [3]
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs.
Papules and plaques of tumid lupus erythematosus can create an annular pattern in certain patients, resembling annular subacute cutaneous lupus erythematosus (SCLE), with less edema at the center. A Blaschkoid distribution, [9] [10] scalp involvement resembling alopecia areata, [11] and periorbital edema are less frequent signs of tumid lupus ...
Cutaneous vasculitis is the most common type of vasulitis amongst those with systemic lupus erythematosus. [7] The clinical presentation is variable and can include superficial ulcerations, splinter hemorrhages, panniculitis, macules, erythema with necrosis or erythematous plaques, cutaneous infarction, livedo reticularis, bullous lesions of the extremities or urticaria lesions, papulonodular ...
There are many conditions which can cause rashes with a similar appearance to a malar rash. [1] These include: lupus erythematosus [3] pellagra [4] dermatomyositis [5] Bloom syndrome [6] Rosacea, a long-term skin condition characterized by a red rash, usually on the face. Lupus causes up to 96% of all cases of malar rash. [3]