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The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus.Regions described in the hippocampus are the head, body, and tail, and other hippocampal subfields include the dentate gyrus, the presubiculum, and the subiculum.
CA3 then fires to CA1 via Schaffer collaterals which synapse in the subiculum and are carried out through the fornix of the brain. Collectively the dentate gyrus, CA1, and CA3 of the hippocampus compose the trisynaptic loop. EC → DG via the perforant path (synapse 1), DG → CA3 via mossy fibres (synapse 2), CA3 → CA1 via schaffer ...
The Schaffer collateral is located between the CA3 region and CA1 region in the hippocampus. Schaffer collaterals are the axons of pyramidal cells that connect two neurons (CA3 and CA1) and transfer information from CA3 to CA1. [5] [6] The entorhinal cortex sends the main input to the dentate gyrus (perforant pathway).
The hippocampus is sometimes called the hippocampus proper and just includes the CA subfields (cornu Ammonis 1-4). The hippocampus, dentate gyrus, and other subfields make up the hippocampal formation. The dentate gyrus contains the fascia dentata and the hilus. The CA is differentiated into subfields CA1, CA2, CA3, and CA4. CA4 is often not ...
The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system.
The hippocampal formation is a compound structure in the medial temporal lobe of the brain. It forms a c-shaped bulge on the floor of the inferior horn of the lateral ventricle. [1] Typically, the hippocampal formation is said to included the dentate gyrus, the hippocampus, and the subiculum. [2]
In mice, the projection to CA1, and the subiculum all come primarily from EC layer III. [citation needed]According to Suh et al. (2011 Science 334:1415) the projection to CA3 and dentate gyrus in mice is primarily from layer II of entorhinal cortex, and forms a trisynaptic path with hippocampus (dentate gyrus to CA3 to CA1), distinguished from the direct (monosynaptic) perforant path from ...
View of left entorhinal cortex (red) from beneath the brain, with front of brain at top. Artist's rendering. The superficial layers – layers II and III – of EC project to the dentate gyrus and hippocampus: Layer II projects primarily to dentate gyrus and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 and the subiculum.