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The US Food and Nutrition Board set a tolerable upper intake level (UL) at 1,000 mg (1,500 IU) per day derived from animal models that demonstrated bleeding at high doses. [30] In the US, the popularity for vitamin E as a dietary supplement peaked around 2000, with popular doses of 400, 800 and 1000 IU/day.
It is most often recommended to obtain vitamin E through a balanced diet because high-dose supplementation may have health risks. [1] There is evidence that the sale of dietary supplement vitamin E has decreased by up to 33% following a report showing little or no effect of vitamin E in preventing cancer or cardiovascular disease.
Tocopherols (/ t oʊ ˈ k ɒ f ə ˌ r ɒ l /; [1] TCP) are a class of organic compounds comprising various methylated phenols, many of which have vitamin E activity. Because the vitamin activity was first identified in 1936 from a dietary fertility factor in rats, it was named tocopherol, from Greek τόκος tókos 'birth' and φέρειν phérein 'to bear or carry', that is 'to carry a ...
Familial isolated vitamin e deficiency; Other names: Ataxia With Vitamin E Deficiency: Familial isolated vitamin E deficiency has an autosomal recessive pattern of inheritance. Specialty: Neurology Treatment: high-dose oral vitamin E supplementation
Vitamin E was named "tocopherol" (from the Greek words tokos, meaning childbirth, and phero, meaning to bring forth) due to its presumed role in aiding conception. Subsequent research identified eight molecules in the vitamin E family, divided into tocopherols and tocotrienols: alpha, beta, delta, and gamma forms. [ 18 ]
For those looking to take a vitamin E supplement or ensure they are reaching the correct amount, Dr. Luke notes that the recommended daily amount of vitamin E is 15 mg/day of α-tocopherol.