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Protein folding problem: Is it possible to predict the secondary, tertiary and quaternary structure of a polypeptide sequence based solely on the sequence and environmental information? Inverse protein-folding problem: Is it possible to design a polypeptide sequence which will adopt a given structure under certain environmental conditions?
Some of the major unsolved problems in physics are theoretical, meaning that existing theories seem incapable of explaining a certain observed phenomenon or experimental result. The others are experimental, meaning that there is a difficulty in creating an experiment to test a proposed theory or investigate a phenomenon in greater detail.
In cosmology, the cosmological constant problem or vacuum catastrophe is the substantial disagreement between the observed values of vacuum energy density (the small value of the cosmological constant) and the much larger theoretical value of zero-point energy suggested by quantum field theory.
The CRC Handbook of Chemistry and Physics is a comprehensive one-volume reference resource for science research. First published in 1914, it is currently (as of 2024 [update] ) in its 105th edition, published in 2024.
For one reason, it is essentially invariant under Galilean transformations, which form the symmetry group of Newtonian dynamics. [note 2] Moreover, processes that change particle number are natural in relativity, and so an equation for one particle (or any fixed number thereof) can only be of limited use. [30]
With respect to classical physics, conservation laws include conservation of energy, mass (or matter), linear momentum, angular momentum, and electric charge. With respect to particle physics, particles cannot be created or destroyed except in pairs, where one is ordinary and the other is an antiparticle.
Ordinary differential equations occur in many scientific disciplines, including physics, chemistry, biology, and economics. [1] In addition, some methods in numerical partial differential equations convert the partial differential equation into an ordinary differential equation, which must then be solved.
The Feynman Lectures on Physics is a physics textbook based on a great number of lectures by Richard Feynman, a Nobel laureate who has sometimes been called "The Great Explainer". [1] The lectures were presented before undergraduate students at the California Institute of Technology (Caltech), during 1961–1964.