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Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Though manuals like the DSM have covered a lot of ground when it comes to defining mental illnesses, in some disorders the reliability of diagnosis is still very poor. For example, inter-rater reliability in cases of dementia is very high, with a kappa value of 0.78, while major depressive disorder is often diagnosed differently by independent experts who see the same patient, with a kappa ...
Drugs is a peer-reviewed medical journal published by Adis International (Springer Nature) that covers topics in drugs and therapeutics. Besides research articles, the journal also publishes "Adis Drug Evaluations and AdisInsight Reports", evidence-based, single-agent reviews.
The Journal Article Tag Suite (JATS) is an XML format used to describe scientific literature published online. It is a technical standard developed by the National Information Standards Organization (NISO) and approved by the American National Standards Institute with the code Z39.96-2012.
The IMRAD format has been adopted by a steadily increasing number of academic journals since the first half of the 20th century. The IMRAD structure has come to dominate academic writing in the sciences, most notably in empirical biomedicine. [2] [6] [7] The structure of most public health journal articles reflects this trend.
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First, what constitutes a "drug" is debatable. For instance, GHB, a naturally occurring substance in the central nervous system is considered a drug, and is illegal in many countries, while nicotine is not officially considered a drug in most countries. Second, the word "abuse" implies a recognized standard of use for any substance.
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