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Scintigraphy (from Latin scintilla, "spark"), also known as a gamma scan, is a diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue (radiopharmaceuticals) are taken internally and the emitted gamma radiation is captured by gamma cameras, which are external detectors that form two-dimensional images [1] in a process similar to the ...
SPECT can be used to complement any gamma imaging study, where a true 3D representation can be helpful, such as tumor imaging, infection imaging, thyroid imaging or bone scintigraphy. Because SPECT permits accurate localisation in 3D space, it can be used to provide information about localised function in internal organs, such as functional ...
The development of single photon emission computed tomography (SPECT), around the same time, led to three-dimensional reconstruction of the heart and establishment of the field of nuclear cardiology. More recent developments in nuclear medicine include the invention of the first positron emission tomography scanner ( PET ).
Coded aperture mask for gamma camera (for SPECT) Scintigraphy ("scint") is the use of gamma cameras to capture emitted radiation from internal radioisotopes to create two-dimensional [1] images. SPECT (single photon emission computed tomography) imaging, as used in nuclear cardiac stress testing, is performed using gamma cameras. Usually one ...
Most recently, technetium-99m scintigraphy has been combined with CT coregistration technology to produce SPECT/CT scans. These employ the same radioligands and have the same uses as SPECT scanning, but are able to provide even finer 3-D localization of high-uptake tissues, in cases where finer resolution is needed.
SPECT (three-dimensional) imaging, as an adjunct to planar methods, may increase sensitivity and accuracy, [2] especially in cases of small parathymic adenomas. By using a gamma camera in nuclear medicine, the radiologist is able to determine if one of the four parathyroid glands is hyperfunctioning, if that is the cause of the hyperparathyroidism.
A bone scan or bone scintigraphy / s ɪ n ˈ t ɪ ɡ r ə f i / is a nuclear medicine imaging technique used to help diagnose and assess different bone diseases. These include cancer of the bone or metastasis , location of bone inflammation and fractures (that may not be visible in traditional X-ray images ), and bone infection (osteomyelitis).
DPD scanning typically uses a gamma camera to obtain SPECT images, with an injection followed by an initial scan after 5 minutes, and a second scan after 3 hours. [3] Images are often scored using the "Perugini system" whereby: [4] [5] Grade 0 – no cardiac uptake and normal bone uptake; Grade 1 – cardiac uptake which is less intense than ...