Search results
Results From The WOW.Com Content Network
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. [3] [6] Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. [7]
Gallstones are more common in pregnant women due to elevated hormones and cholesterol levels, which block the bile duct and obstruct bilirubin excretion. [11] Besides, preeclampsia and eclampsia , denoted by high blood pressure , are linked to hyperbilirubinemia through damaging highly perfused organs , particularly liver and kidneys . [ 12 ]
The underlying causes of hemolytic jaundice, as its name suggests, are disorders associated with hemolysis. Such disorders are manifold and the common causes include: Blood smear of a patient with sickle cell disease. The characteristic sickle-shaped appearance of red blood cells can be observed.
Over time, when red blood cells need to be replenished, the hemoglobin is broken down in the spleen; it breaks down into two parts: heme group consisting of iron and bile, and protein fraction. While protein and iron are utilized to renew red blood cells, pigments that make up the red color in blood are deposited into the bile to form bilirubin ...
Gilbert syndrome has been reported to contribute to an accelerated onset of neonatal jaundice. The syndrome cannot cause severe indirect hyperbilirubinemia in neonates by itself, but it may have a summative effect on rising bilirubin when combined with other factors, [10] for example in the presence of increased red blood cell destruction due ...
The study found that 15.3% of participants had mild cognitive impairment, and that women with mild cognitive impairment were more likely to report more severe menopause symptoms.
Treatment depends on the type and cause of the hemolytic anemia. [2] Symptoms of hemolytic anemia are similar to other forms of anemia (fatigue and shortness of breath), but in addition, the breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones [4] and pulmonary hypertension. [5]
Physical examination findings typically include jaundice and right upper quadrant tenderness. [1] Charcot's triad is a set of three common findings in cholangitis: abdominal pain, jaundice, and fever. [4] This was assumed in the past to be present in 50–70% of cases, although more recently the frequency has been reported as 15–20%. [1]