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  2. Esketamine - Wikipedia

    en.wikipedia.org/wiki/Esketamine

    Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [ 5 ] [ 13 ] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression .

  3. FDA-approved nasal spray for severe depression can lead to ...

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    Additionally, by the fourth week of the study, 22.5% of participants taking 84 milligram (mg) doses of Spravato achieved MDD remission with an MADRS total score of less than or equal to 12, and 18 ...

  4. Does Medicare cover ketamine infusions for mental health ...

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    Medicare does not typically cover ketamine infusions for mental health conditions. However, it may cover Spravato, an FDA-approved drug deriving from ketamine, for treatment-resistant depression.

  5. Breakthrough antidepressants with fewer side effects could ...

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    Ketamine is a sedative and it can cause dissociation—that is, a disconnect from your body, mind, and reality, like a drug trip. It has the potential for abuse, too. Ketamine is also known as the ...

  6. Thousand-yard stare - Wikipedia

    en.wikipedia.org/wiki/Thousand-yard_stare

    The thousand-yard stare (also referred to as two-thousand-yard stare) is the blank, unfocused gaze of people experiencing dissociation due to acute stress or traumatic events. It was originally used about war combatants and the post-traumatic stress they exhibited but is now also used to refer to an unfocused gaze observed in people under a ...

  7. Psychoplastogen - Wikipedia

    en.wikipedia.org/wiki/Psychoplastogen

    Esketamine, sold under the brand name Spravato and produced by Janssen Pharmaceuticals, was approved by the FDA in March 2019 for the treatment of Treatment-Resistant Depression (TRD) and suicidal ideation. [8] As of 2022, it is the only psychoplastogen approved in the US for the treatment of a neuropsychiatric disorder. [6]

  8. Dissociation (psychology) - Wikipedia

    en.wikipedia.org/wiki/Dissociation_(psychology)

    Dissociation is commonly displayed on a continuum. [18] In mild cases, dissociation can be regarded as a coping mechanism or defense mechanism in seeking to master, minimize or tolerate stress – including boredom or conflict. [19] [20] [21] At the non-pathological end of the continuum, dissociation describes common events such as daydreaming.

  9. Dissociative disorder - Wikipedia

    en.wikipedia.org/wiki/Dissociative_disorder

    A second area of discussion surrounds the question of whether there is a qualitative or quantitative difference between dissociation as a defense versus pathological dissociation. Experiences and symptoms of dissociation can range from the more mundane to those associated with post traumatic stress disorder (PTSD) or acute stress disorder (ASD ...

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