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2,4-Dinitrophenylhydrazine (2,4-DNPH or DNPH) is the organic compound C 6 H 3 (NO 2) 2 NHNH 2. DNPH is a red to orange solid. It is a substituted hydrazine. The solid is relatively sensitive to shock and friction. For this reason DNPH is usually handled as a wet powder. DNPH is a precursor to the drug Sivifene.
2,4-Dinitrophenol (2,4-DNP or simply DNP) is an organic compound with the formula HOC 6 H 3 (NO 2) 2. It has been used in explosives manufacturing and as a pesticide and herbicide. In humans, DNP causes dose-dependent mitochondrial uncoupling , causing the rapid loss of ATP as heat and leading to uncontrolled hyperthermia —up to 44 °C (111 ...
Once the presence of a carbonyl group has been identified using 2,4-dinitrophenylhydrazine (also known as Brady's reagent or 2,4-DNPH or 2,4-DNP), Tollens' reagent can be used to distinguish ketone vs aldehyde. Tollens' reagent gives a negative test for most ketones, with alpha-hydroxy ketones being one exception.
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Frederick Sanger. In 1945, Frederick Sanger described its use for determining the N-terminal amino acid in polypeptide chains, in particular insulin. [4] Sanger's initial results suggested that insulin was a smaller molecule than previously estimated (molecular weight 12,000), and that it consisted of four chains (two ending in glycine and two ending in phenylalanine), with the chains cross ...
2,4-DNP can mean: 2,4-Dinitrophenol, a small organic molecule formerly marketed as a pharmaceutical "diet aid" 2,4-Dinitrophenylhydrazine, Brady's reagent, used in ...
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2,4-Dinitrophenol, a small organic molecule formerly marketed as a pharmaceutical "diet aid" Deoxyribonucleoprotein, a complex of DNA and protein; Distance to neutral point, a quantity which is important when considering thermal expansion mismatch