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In bioinformatics, neighbor joining is a bottom-up (agglomerative) clustering method for the creation of phylogenetic trees, created by Naruya Saitou and Masatoshi Nei in 1987. [1] Usually based on DNA or protein sequence data, the algorithm requires knowledge of the distance between each pair of taxa (e.g., species or sequences) to create the ...
Masatoshi Nei was born in 1931 Japan, and his lifelong interest in biology and genetics may have its roots in his upbringing on a farm, in a family of farmers. [1] After completing his undergraduate and doctorate degrees in Japan, Nei emigrated to the United States in 1969. [ 1 ]
Nei's D A distance was created by Masatoshi Nei, a Japanese-American biologist in 1983. This distance assumes that genetic differences arise due to mutation and genetic drift , but this distance measure is known to give more reliable population trees than other distances particularly for microsatellite DNA data.
MEGA offers several approaches for testing substitution pattern homogeneity, such as composition distance, disparity index, and Monte Carlo tests. These methods are used to determine if different genetic regions evolved under the same selective pressure. Computation distance measures the variation in nucleotide composition between two sequences.
In genetics, a centimorgan (abbreviated cM) or map unit (m.u.) is a unit for measuring genetic linkage. It is defined as the distance between chromosome positions (also termed loci or markers) for which the expected average number of intervening chromosomal crossovers in a single generation is 0.01. It is often used to infer distance along a ...
Nucleotide diversity is a measure of genetic variation. It is usually associated with other statistical measures of population diversity, and is similar to expected heterozygosity . This statistic may be used to monitor diversity within or between ecological populations, to examine the genetic variation in crops and related species, [ 3 ] or to ...
This method was presented by Cornuet et al. in 1999. [4] It uses genetic distance to assign the individual to the “closest” population. For the interpopulation distances, the individual is assigned as a sample of two alleles; for the shared allele distance, the distance was taken as the average of distances between the individual and the population samples.
The mediaeval great chain of being as a staircase, implying the possibility of progress: [1] Ramon Lull's Ladder of Ascent and Descent of the Mind, 1305. Alternatives to Darwinian evolution have been proposed by scholars investigating biology to explain signs of evolution and the relatedness of different groups of living things.