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Preclinical imaging is the visualization of living animals for research purposes, [1] such as drug development. Imaging modalities have long been crucial to the researcher in observing changes, either at the organ, tissue, cell, or molecular level, in animals responding to physiological or environmental changes.
The Quality of Life of Carers of Alzheimer's Disease Patients (ACQLI) is a measure which assesses the quality of life of people who care for Alzheimer's disease patients. It was developed in 1997 by Galen Research [1] and has been used in studies investigating rosiglitazone [2] [3] [4] and the effects of pharmacological treatment. [5] Angina.
In Fluorescence lifetime and spectral imaging, phasor can be used to visualize the spectra and decay curves. [1] [2] In this method the Fourier transformation of the spectrum or decay curve is calculated and the resulted complex number is plotted on a 2D plot where the X-axis represents the real component and the Y-axis represents the imaginary ...
Fluorescence imaging with one nanometer accuracy (FIONA): utilizes total internal reflection illumination to reduce noise and increase brightness of fluorophores [5] Calcium imaging: technique that utilizes fluorescent molecules called calcium indicators that change in fluorescence when bound to Ca 2+ ions. This is a key part in seeing when ...
The self-perceived quality-of-life scale [1] [2] is a psychological assessment instrument which is based on a comprehensive theory of the self-perceived quality of life (SPQL) [3] and provides a multi-faceted measurement of health-related and non-health-related aspects of well-being. [4]
Fluorescence-lifetime imaging microscopy or FLIM is an imaging technique based on the differences in the exponential decay rate of the photon emission of a fluorophore from a sample. It can be used as an imaging technique in confocal microscopy , two-photon excitation microscopy , and multiphoton tomography.
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